Headache,Migraine,Trigeminal Neuralgia,Fibromyalgia,Herpes zoster Neuralgia
BIOCEPHAL is a natural supplement with the properties of an herbal product. It's made up of
Niacinamide, Riboflavin, Rhodiola Rosea and Vitis Vinifera. Biocephal has no side effects,
does not accumulate in the body, has no interactions with any drug or contraindications.
Gluten and lactose free
Contents
1 Headache, Migraine, Trigeminal neuralgia
6 Mechanism of Headaches, trigeminal neuralgia, Fibromyalgia
In all of the following diseases, the first significant benefits will begin to be seen in many cases already
after a few days or within 15 days of starting treatment.
The reactive diseases are Primary Headaches (Migraine without / with aura, aura without migraine,
cluster headache, tension-type headache, hemiplegic migraine, menstrual headache).
Other reactive pathologies are Trigeminal neuralgia, Post-herpetic neuralgia (St. Anthony's fire),
Fibromyalgia, intercostal neuralgia.
Due to individual variability, the indicated improvement terms may be delayed by 1 month.
Nature loves Simple Solutions (William of Ockham)
The powerful antioxidant activity of Rhodiola Rosea and Vitis vinifera stabilize the production of
neurotransmitters. In this way, they counteract free radicals that damage nerve cells and effectively
counteracts the biochemical mechanisms underlying reactive diseases, due to the disordered release of
neuromediators from mast cells.
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Biocephal was tested at the Headache Center of S. Carlo di Nancy Hospital of Rome (Dir.Prof.D.Moscato).
Presented at the XXII Congress of Italian Society for the Study of Headaches (SISC). Published in
"J.Headache Pain" 2008-pages 55-56.
QUALITY FIRST!
BIOCEPHAL by Green Bios. Box 30 caps. Retail price € 13,00. In pharmacy without prescription.
Store below 30 ° C. Notificated to Italian Ministry of Health 10/02/2016.
Made in Italy production plant: R.E.F. – Roma Via Tor Sapienza,211.
No dyes added! We eliminated dye from the capsules to have a more natural product
(the dye is allowed by the Ministry of Health for food products).
A Product to be Free
Posological Indications:
Headache, Migraine, Trigeminal neuralgia: Adults: 1 cps. after breakfast and 2 capsules after lunch for 3
months. Subsequently, once healing is achieved, 2 cps. a day continuously.
Affected people over 80 kg (176 lbs.) or age over 65: 2 cps. after breakfast and 2 capsules after lunch for 3
months. Subsequently, once healing is achieved, 2 cps. a day, continuously.
Children under 30 kg(66 lbs): one capsule a day for 3 months. Thereafter, 1 capsule per day for 15 days each
month (the capsules can be opened and poured into water or milk).
Children that weigh between 30 and 40 kg.(88 lbs), 2 capsules a day for 3 months. Thereafter, 1 capsule a day
continuously. Children weighing over 40 kg. Dose like rhe adults.
Cluster headache (in case of pain): two capsules after breakfast and two capsules after lunch for 3 months
or until the pain subsides.
Weight over 80 kg.(176 lbs) or over 65 years of age take two capsules after breakfast, lunch and dinner
(6 caps per day) for 3 months or until the pain subsides.
Cluster headache (prevention): once the pain of initial phase (acute stage) disappeared, take 2 capsules a day,
continuously. If, during the maintenance period, in the cold season, a reappearance of the symptoms were to
be have, 2 cps are toke after breakfast and 2 cps after lunch for a month and then continue with 2 cps a day.
Headache by DAO lack: Adults: 1 cps. after breakfast and 2 capsules after lunch for 3 months. Subsequently,
once healing is achieved, 2 cps. a day, continuously.
Affected people over 80 kg. (176 lbs) or age over 65: 2 cps. after breakfast and 2 capsules after lunch for 3 months.
Subsequently, once healing is achieved, 2 cps. a day, continuously.
and...it's just life coming in
Fibromyalgia: 1 cps. after breakfast and 2 capsules after lunch for 6 months. Then, 2 cps. a day continuously.
Affected people over 80 kg. (176 lbs) or age over 65: 2 cps. after breakfast and 2 capsules after lunch for 4 months.
Then, 1 capsule after breakfast and 2 capsules after lunch for another 3 months. Subsequently, 2 cps. a day, continuously.
Post-herpetic neuralgia, Intercostal neuralgia: Adults:one capsule after breakfast and two capsules after lunch
for 45 days. Then, 1 capsule after breakfast and 1 cps. after lunch for other 45 days. Subsequently, once healing is
achieved, one cps a day, continuously.
Weight over 80 Kg. (176 lbs.)or age over 65 years: two capsules after breakfast and two capsules after lunch for 45
days .Then, 1 capsule after breakfast and 2 cps. after lunch for other 45 days. Subsequently, once healing is achieved,
two cps. a day continuously.
Europe Pat. n.1318815
USA Pat. n.7,456,291 B2
Russia - Eurasian Pat. n.RU 2274448
China Pat. n. 01813823.3
Canada Pat. n. 2.417.758
MECHANISM of HEADACHE, TRIGEMINAL Neuralgia, FIBROMYALGIA
Onset of migraine and trigeminal neuralgia is determined by a neurogenic inflammation in trigemino-vascular circuit.
This is caused by release of biochemical mediators from mast cells. The stimulation of the meningeal structures and
large cerebral vessels causes pain due to the activation of the unmyelinated fibers, from which they are innervated.
During a migraine or trigeminal neuralgia, there is a leakage of blood plasma proteins and the development of an
inflammation of intracranial vessels. This is caused by an abnormal triggering of mast cells and subsequent activation
of trigeminal innervation. So, you have a violent entry in the blood of peptide neurotransmitters to vasodilator effect.
They are contained in the nerve fibers of the trigemino-vascular system. These neurotransmitters are represented by
CGRP (calcitonin gene-related peptide), leukotrienes, neurokinins, histamine.
Fibromyalgia is a chronic, idiopathic condition of widespread musculoskeletal pain that affects more women than men.
Substance P is a neuromediator involved in onset of this disease. Function of substance P is to cause the release of
inflammatory cytokines such as interleukin 6 and TNF from mast cells. This contributes significantly to symptoms of
fibromyalgia.
Riboflavin and Niacinamide play an important role in mast cell metabolism and act as coenzymes. Their shortage
negatively affects the production of energy within mast cells. This lack lowers the energy of mast cells, leading to their
disordered activation. This activation causes the excessive release of neurotransmitters and biochemical mediators.
Rhodiola rosea and Vitis vinifera are among the most powerful natural antioxidants known and, then, have
extraordinary activity against free radicals.
These antioxidant activities have a double effect: they provide direct neuroprotection against oxidative stress and
indirect protection through the suppression of inflammation. Therefore, the action of these two natural substances is
expressed both in an effective stabilizing action of cell membranes and in a correct development of tissues breating.
Activity of these natural substances, together with the action of previous coenzymes, normalizes the blood
microcirculation and balances the mood.
